skip to main
For US Healthcare Professionals Only
Image of a blueprint of the Mona Lisa asking 'What lies beneath in DDLPS?'.

What lies beneath in DDLPS?

DDLPS=dedifferentiated liposarcoma.

WHEN YOU LOOK DEEPER,

The secret of DDLPS reveals excess MDM2

Below the surface of this disease, p53 is being disrupted by excess MDM2

For nearly 50 years, the standard of care for locally advanced (unresectable) and/or metastatic DDLPS has not changed significantly. DDLPS is a liposarcoma subtype that poses a formidable challenge characterized by its local recurrence rates and poor overall prognosis.1-5

MDM2=mouse double minute 2.

Download HCP brochure
References:

  1. Italiano A. Cancer Discov. 2023;13(8):1765-1767.

  2. Gahvari Z, Parkes A. Curr Treat Options Oncol. 2020;21(2):15. doi:10.1007/s11864-020-0705-7

  3. Langmans C, Cornillie J, van Cann T, et al. Oncol Res Treat. 2019;42(7-8):396-403.

  4. McGovern Y, Zhou CD, Jones RL. Front Oncol. 2017;7:292. doi:10.3389/fonc.2017.00292

  5. Nguyen K, Gootee J, Aurit S, Albagoush S, Curtin C, Silberstein P. Surg Case Rep. 2021;4(2):7-7. doi:10.31487/j.SCR.2021.02.02

  6. Shaikh MF, Morano WF, Lee J, et al. Ann Clin Lab Sci. 2016;46(6):627-634.

  7. Kung CP, Weber JD. Front Cell Dev Biol. 2022;10:818744. doi:10.3389/fcell.2022.818744

  8. Gamboa AC, Gronchi A, Cardona K. CA Cancer J Clin. 2020;70(3):200-229.