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Image of a blueprint of the Mona Lisa with text overlay 'Looking deeper into DDLPS'.

Looking deeper into 
DDLPS

DDLPS=dedifferentiated liposarcoma.

What do you see when you look deeper?

Soft tissue sarcoma (STS) accounts for about 1% of all adult malignancies. There are more than 100 different histologic subtypes, and each subtype has a unique clinical behavior.1

  • Liposarcomas represent the predominant subtype of STS, comprising 15-20% of all cases2

  • Among liposarcomas, DDLPS represents 15-20% of diagnosed cases2

Estimated proportion of liposarcoma2

Charts showing the estimated proportion of liposarcoma in STS is 15-20%, and among liposarcomas, DDLPS represents 15-20% of diagnosed cases.

DDLPS is an aggressive subtype of liposarcoma with poor prognosis3

DDPLS occurs de novo in 90% of cases and in 10% as a recurrence from pre-existing WDLPS cases.4

Graphic showing that about 1000 new Dedifferentiated Liposarcoma (DDLPS Cancer) and WDLPS (Well-differentiated liposarcoma) cases are diagnosed each year in the US.
Graphic showing the current recurrence rate for Dedifferentiated Liposarcoma (DDLPS Cancer) at approximately 40%.
Graphic showing the metastatic rate in Dedifferentiated Liposarcoma (DDLPS Cancer) at 15 - 30%
Patient with metastatic DDLPS playing the guitar with a cat next to him

MLPS=myxoid/round-cell liposarcoma; PLPS=pleomorphic liposarcoma; STS=soft tissue sarcoma; WDLPS=well-differentiated liposarcoma.

References:

  1. Gamboa AC, Gronchi A, Cardona K. CA Cancer J Clin. 2020;70(3):200-229.

  2. Schöffski P. Oncol Res Treat. 2022;45(9):525-543.

  3. Gahvari Z, Parkes A. Curr Treat Options Oncol. 2020;21(2):15. doi:10.1007/s11864-020-0705-7

  4. Sciot R. Diagnostics. 2021;11(3):496. doi:10.3390/diagnostics11030496

  5. Gounder M, Abdul Razak AR, Gilligan AM, et al. Future Oncol. 2021;17(22):2923-2939.